Manchester City will face Paris Saint-Germain in the quarter-finals of the Champions League.
City avoided incoming manager Pep Guardiola’s Bayern Munich and title holders Barcelona, who have knocked them out in the past two seasons.
PSG, who have already been crowned French champions this season will host the first leg at the Parc des Princes.
Barcelona, attempting to become the first side to win back-to-back Champions League title, face an Atletico side they have enjoyed playing in recent seasons.
The Spanish champions are eight points clear of second-placed Atletico in the La Liga, having beaten them in both league matches this season.
Ten-time champions Real Madrid, who overcame Roma to get through to the last eight, were pitted against German side VfL Wolfsburg.
Bayern Munich will face Portuguese champions Benfica. It is the first time since 1976 that both teams will meet.
Meanwhile, Jurgen Klopp will return to Borussia Dortmund for the first time as Liverpool manager after the clubs were drawn together in the Europa League quarter-finals.
It will be the first time Klopp returns to the Westfalenstadion after deciding to leave Dortmund at the end of the 2014-15 season following a seven-year stint with the club.
UEFA Europa League (@EuropaLeague) March 18, 2016